December 18, 2007

We are become gods.

Posted by apostropher

So much potential, both positive and negative. But undeniably fascinating.

Scientists in Maryland have already built the world's first entirely handcrafted chromosome -- a large looping strand of DNA made from scratch in a laboratory, containing all the instructions a microbe needs to live and reproduce. In the coming year, they hope to transplant it into a cell, where it is expected to "boot itself up," like software downloaded from the Internet, and cajole the waiting cell to do its bidding. And while the first synthetic chromosome is a plagiarized version of a natural one, others that code for life forms that have never existed before are already under construction.

The cobbling together of life from synthetic DNA, scientists and philosophers agree, will be a watershed event, blurring the line between biological and artificial -- and forcing a rethinking of what it means for a thing to be alive. [...]

LS9 Inc., a company in San Carlos, Calif., is already using E. coli bacteria that have been reprogrammed with synthetic DNA to produce a fuel alternative from a diet of corn syrup and sugar cane. So efficient are the bugs' synthetic metabolisms that LS9 predicts it will be able to sell the fuel for just $1.25 a gallon.

At a DuPont plant in Tennessee, other semi-synthetic bacteria are living on cornstarch and making the chemical 1,3 propanediol, or PDO. Millions of pounds of the stuff are being spun and woven into high-tech fabrics (DuPont's chief executive wears a pinstripe suit made of it), putting the bug-begotten chemical on track to become the first $1 billion biotech product that is not a pharmaceutical.

Worth reading all the way through. Via Carl Zimmer.


Comments
1

Wow.

I can see it now, a chromosome engineered at UNLV which, when implanted into the subject, causes a local melanin concentration in the shape of the goldenpalace.com logo.

Posted by: Cangrejero at December 18, 2007 02:45 PM
2

It is pretty impressive stuff -- synthetic biology is the Hot Topic nowadays in a lot of places.

At the same time, it's worth remembering: not all "chromosomes" are created equal. This is another way of saying that, it's one thing to do this for bacteria, and a completely different thing to do this for for a more complex organism. We don't even understand yeast well enough (not even close!) to build something like them, and they're still single-celled. Once you start considering multicellular organisms, that's another degree of magnitude. Vertebrates, yet another level. Humans, another level yet.

It's going to be a long time before you see this move out of the realm of bacteria.

(There's also the question of how much we're 'creating' new life here, vs. 'copying' things we've seen elsewhere, but maybe that's a different question.)

Posted by: arthegall at December 18, 2007 02:52 PM
3

DuPont - lovely
http://www.corporatewatch.org/?lid=173

Posted by: waldo at December 18, 2007 08:41 PM
4

Yeah, evidence for Intelligent Design can be found both near and far ....

Posted by: TokyoTom at December 18, 2007 09:23 PM
5

Boys and girls, your homework for Christmas break is to watch the Resident Evil trilogy.

Posted by: gswift at December 19, 2007 01:50 AM
6

Next thing you know, they'll be make three pound rats.

Posted by: caradoc at December 20, 2007 10:52 AM
7

I'm betting that this development will be a positive one for the human race.

Posted by: Jon at December 20, 2007 10:59 PM
Post a comment









Remember personal info?